Taro (Colocasia Esculenta (L.) Schott) Extract didn’t Increase Superoxide Dismutase (SOD) but Decrease C-Reactive Protein (CRP) in Male Wistar Rat (Rattus Norvegicus) Diabetes Mellitus Model

Backgrounds: In hyperglycemia induced by streptozotocin, free radicals and oxidative stress conditions occur. This also reduced SOD enzymes while increasing CRP. study aimed to analyze effect of flavonoid-rich taro leaves ethanol extract on levels serum CRP in rats diabetes melitus model streptozotocin. Methods: Experimental with a pretest-posttest control group design 26 healthy were randomly divided into 2 groups. The was given ml aquadest treatment 400mg/kgBW aquadest. Before after treatment, blood collected for analysis using the ELISA technique. Results: level goup before plasebo reduce insignificantly (from 5.37?0.69 ng/ml 5.26?1.50 ;p = 0.830). Furthermore, not signifcantly different 3.39?0.24 3.56 ?0.43 ; p 0.308). increase but significant 5.33 ?1.14 6.20 ?2.64 ng/mL; 0.239). However, decrease significantly ? 0.43 ng/mL 2.93 0.47 nmol/mL 0.009).Conclusion: did Further studies are needed confirm as external antioxidant.